+1-315-636-4485
+91 98151-74050 
This quiz contains multiple-choice problems on genome mapping and sequencing, genome sequence assembly, genome annotation and comparative genomics.
Which of the following is incorrect regarding genome mapping?
It does not lead to the understanding of a genome structure
It involves identifying relative locations of genes
It involves identifying traits
It involves identifying mutations
Genetic markers are __ portions of a __ whose inheritance patterns can be followed.
unidentifiable, genes
unidentifiable, chromosome
identifiable, chromosome
identifiable, genes
Genetic linkage maps, also called genetic maps, identify the relative positions of genetic markers on a chromosome and are based on how frequent the markers are inherited together. True or false?
True
False
One centimorgan is defined as __ percentage of the total recombination events.
One
Ten
0.1
0.01
Physical maps are locations maps of identifiable landmarks on genomic DNA __ inheritance patterns.
Remotely related to
Related to
Regardless of
Associated with
Physical maps are constructed using a chromosome walking technique. True or false?
True
False
Which of the following is incorrect regarding cytologic maps?
They cannot be directly observed under microscope
They refer to banding patterns
They can be viewed on stained chromosomes
They can be directly observed under microscope
Cytologic maps can be considered of __ resolution and somewhat __ physical maps.
very high, inaccurate
very low, accurate
very high, accurate
very low, inaccurate
In medical applications, the ultimate goal of gene mapping is to disease genes. True or false?
True
False
One of the fundamental events in meiosis is crossing over in which homologous chromosomes exchange segments causing a reshuffling of genes. True or false?
True
False
Which of the following is incorrect regarding base calling and assembly programs?
The first step toward genome assembly includes derive base calls
The first step toward genome assembly includes assigning associated quality scores
One of the steps is to assemble the sequence reads into contiguous sequences
There is no identifying overlap between sequence fragments
Which of the following is incorrect about Phred?
It is a UNIX program
It does not give a probability score in output
It is used for base calling
It uses a Fourier analysis to resolve fluorescence traces and predict actual peak locations of bases
Which of the following is incorrect about Phrap?
It aligns individual fragments in a pairwise fashion using the Smith–Waterman algorithm
It does not take input from Phred
It is used for sequence assembly
It is a UNIX program
VecScreen is primarily aimed at sequence assembly. True or false?
True
False
Which of the following is incorrect about EULER?
It is an assembly algorithm
It uses a Eulerian Superpath approach, which is a polynomial algorithm
In this approach, a sequence fragment is broken down to tuples of five nucleotides
The tuples are distributed in a diagram with numerous nodes that are all interconnected
