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This presentation gives an overview of the topics mentioned below:
1. Heredity
2. Trait
3. True-breeding or purebred
4. Self-pollination
5. Cross-pollination
Mendel's Laws
1.
Our story begins in the far away land now know as the Czech
Once upon a time, there lived a poor peasant family. They had
a son. His name was Gregor.
Gregor was smart, inquisitive.
He grew up to become a monk and taught high school.
At the monastery, he inherited a garden of purebred peas.
Curiosity got the better of Gregor and he started
experimenting with his peas.
One of his primary pursuits was the study of the effect of
crossbreeding on different strains of pea plants.
This was the beginning of the science we now know as
2.
This is the story of Gregor Mendel – the Father of Modern
Genetics
Cute site to virtually experiment with
peas like Mendel
3.
Genetics is the study of heredity.
Heredity is the passing of traits from parents to their
A trait is a characteristic that a living thing can pass
on to its young.
It (genetics) explains how certain characteristics are
passed on from parents to children.
Mendel worked exclusively with true-breeder pea
plants. This means…
True-breeding or purebred – belonging to a group
of organisms that can produce offspring having only
one form of a trait in each generation.
4.
Normally, pollen from the male part of the pea flower
fertilizes the female egg cells of the very same flower.
Because the pollen produced by the plant fertilizes the
egg of the very same plant, peas are said to produce
sees by
Self Pollination – the process in which pollen falls
from the anther to the stigma of the same flower or
between flowers of the same plant.
Seeds produced by self pollination inherit all of their
characteristics from the single plant that bore them.
5.
Mendel learned that self pollination could be
He carefully cut male parts off all the flowers of one
plant and female parts off all the flower of another
He then pollinated the two plants by dusting the pollen
from one plant onto the flowers of the other plant.
Fertilization of plants egg by pollen by another plant is
Cross Pollination – Transfer of pollen from the
flower of one plant to the flower of a different plant.
8.
Cross pollination produced seeds that are the offspring of
two different plants and Mendel was able to cross plants with
different characteristics.
9.
The F1 generation of peas, because they had the genes
(or alleles) for two different traits,were called
Hybrids
In other words,
These offspring were heterozygous.
Heterozygous – organisms resulting from a cross
between dissimilar parents
10.
Because the parental generation (the P generation)
were the products of two parents with the same traits
(or alleles), the P generation was
HOMOZYGOUS
Homozygous – Organism that has two (2) identical
alleles for a particular trait
An ALLELE – one of a number of different forms of
the SAME GENE for a specific trait
A GENE – a segment of DNA that codes for a
particular protein (hence a trait or characteristic). it is
the basic unit of heredity.
11.
Through his work with peas, Mendel came up with
three principles:
•The Law of Dominance
•The Law of Segregation
•The Law of Independent Assortment
12.
The Law of Dominance
The principle of dominance states that some alleles
are dominant and others are recessive
An organism with a dominant allele for a particular form of a trait
will always have that form.
Dominant: form of a gene (allele) that is expressed
even if present with the contrasting recessive allele.
They overpower the expression of the other form of
the allele.
Always use an uppercase letter to represent the
dominant allele.
13.
An organism with a recessive allele for a particular form of a trait will
have that form only when the dominant allele for the trait is not present
Recessive – Description of a form of a gene (allele)
that is only expressed in the homozygous state.
Always use a lower case letter to represent the
recessive allele.
In Mendel’s experiments, the allele for tall plants was dominant
and the allele for short plants was recessive.
In his first experiments, Mendel looked at only one trait at a time.
14.
This type of cross is called a monohybrid cross.
We’re looking at only ONE trait.
A simple way to represent a cross is to set up a
Punnett square.
It is a chart showing the possible combinations of
genes in the offspring of a cross.
15.
P generation
T T
t T t Tt
t T t Tt
16.
F1 generation
T t
T T T Tt
t T t t t
17.
Physical characteristics of an organism.
What the organism physically looks like
How the genes are expressed.
Ex.: Pea plants with Tt are always Tall – look at them
– they are tall. You can SEE the trait.
What the genes look like – the genetic makeup of an
Ex.: a heterozygous tall pea plant would have the
genes (alleles) T and t (Tt)
A homozygous tall pea plant would have the alleles T
and T (TT)
19.
One of the offspring was a short pea plant!!!!
The short pea trait reappeared in the F2 generation.
How did that happen???
Once again, the alleles separated and recombined to
produce a new combination
The cross resulted in one pair of recessive alleles, tt.
Although all of the F1 plants appeared to be tall, the
alleles separated and recombined during the cross.
20.
This is an example of the LAW OF SEGREGATION.
Segregation – the separation; in genetics, the
separation of alleles during gamete formation.
When each F1 plant flowers, the two alleles are
segregated from each other so that each gamete
carries only a single copy of each gene. Therefore,
each F1 plant produces two types of gametes—those
with the allele for tallness and those with the allele
for shortness
22.
Whenever Mendel performed a cross with pea plants, he carefully
counted the offspring. Every time Mendel repeated a particular cross, he
obtained similar results. For example, whenever Mendel crossed two
plants that were hybrid for stem height (Tt), about three fourths of
the resulting plants were tall and about one fourth were short.
Mendel realized that the principles of probability could be used to
explain the results of genetic crosses
Probability - the likelihood that a particular event
will occur
Ex.: flipping a coin
2 possible outcomes
1 in 2 chance it will be heads (or 50% chance)
1 in 2 chance it will be tails (or 50% chance)
23.
Flip a coin three times in a row, what is the probability
that it will land heads up?
Because each coin flip is an independent event, the
probability of each coin’s landing heads up is 1/2
Therefore, the probability of flipping three heads in a
row is:
The principles of probability can be used to predict
the outcomes of genetic crosses.
24.
The calico cat
3 main colors – black, orange and white.
White is due to a single gene difference.
The black and orange are due to X chromosome inactivation
part of the X chromosomes are inactivated).
Hairy ear rims.
Caused by an allele of a Y-linked gene.
25.
Did alleles segregate independently.
Does the segregation of one pair of alleles affect the
segregation of another pair of alleles?
For example, does the gene that determines whether a seed
is round or wrinkled in shape have anything to do with the
gene for seed color?
Must a round seed also be yellow?
To answer his questions, Mendel crossed purebred
plants that produced Round Yellow Seeds with
purebred plants that produced Wrinkled Green Seeds
26.
The 2-Factor Cross: F1 Generation (two traits)
Round yellow seeds RRYY
Wrinkled green seeds rryy
An RY gamete and an ry gamete combine to form a
fertilized egg with a genotype RrYy
28.
Only one kind of plant will show up in the F1 generation –
heterozygous or hybrid for both traits.
The phenotype of the F1 ge3neration will be all round and
Round and Yell are both dominant
Cross the F1 plants wit each other. What will happen?
If the genes for seed shape and color are connected in some
way, then the dominant R and Y alleles and the recessive r and
y alleles will be segregated as MATCHED sets into the
If the genes are NOT connected, then they should segregate
independently or undergo INDEPENDENT ASSORTMENT.
30.
Mendel’s 3rd law
The Law of Independent Assortment
states:
Genes for different traits can segregate
independently during the formation of gametes
31.
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32.
A Summary of Mendel’s Principles
•The inheritance of biological characteristics is determined by
individual units known as genes. In organisms that reproduce
sexually, genes are passed from parents to their offspring.
•In cases in which two or more forms of the gene for a single trait
exist, some forms of the gene may be dominant and others may be
•In most sexually reproducing organisms, each adult has two
copies of each gene—one from each parent. These genes are
segregated from each other when gametes are formed.
•The alleles for different genes usually segregate independently of
one another.
33.
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34.
Some alleles are neither dominant nor recessive,
and many traits are controlled by multiple alleles
or multiple genes.
35.
Co Dominance
Sometimes you’ll see an equal expression of both
Ex.: roan coat in cattle
If one parent has a red coat, RR, and the other parent
has a white coat, WW, the offspring will have a roan
coat. RW
BOTH ALLELES ARE EXPRESSED.
36.
Multiple Alleles
Sometimes the expression of a trait involves more
than two alleles
Ex.: two genes are involved in the expression of AB
blood group
A combination of genes determine the different blood
types (A, B, AB, O)
In the case of the AB blood type, BOTH A and B are
39.
GREEN EYES
Eye color comes from a combination of two black and
yellow pigments called melanin in the iris of the eye. If
you have no melanin in the front part of your iris, you
have blue eyes. An increasing proportion of the yellow
melanin, in combination with the black melanin, results in
shades of colors between brown and blue, including green
and hazel.
Generally, brown eye genes are dominant over green eye
genes which are both dominant over blue eye genes.
However, because many genes are required to make each
of the yellow and black pigments, there is a way called
genetic compensation to get brown or green eyes from
blue-eyed parents.
40.
Coat color inheritance in Labrador retrievers.
2 alleles b and B, of a pigment gene, determine black and brown
At a separate gene, E allows color deposition in the coat, and ee prevents
deposition, resulting in a gold phenotype
This is a case of recessive epistasis (canceling out genes).
Thurs there are three homozygous genotypes: BBEE, BbEE, Bbee or
The ability to make black pigment, as witnessed by a black nose on a
gold retriever, but not to deposit this pigment on the hairs is probably
41.
Intermediate Inheritance or
Incomplete Dominance
Not all patterns of inheritance obey the principles of
Mendelian genetics.
In fact, many traits occur due to a combined
expression of alleles.
Ex.: Crossing pure red (RR) and pure white (WW)
Japanese four-’clocks results in flowers that are all
pink (RW)
To know if something is dominant, co dominant or
incomplete dominance, you must look at the
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